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 Post subject: fermented wheat germ
PostPosted: Sat Dec 17, 2022 4:53 pm 
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Preparation of FWGE:

Thirty grams of active Saccharomyces cerevisiae cells were suspended in 270ml distilled water and mixed with 90g of wheat germ.The mixture was then fermented at 37ÂșC for 48hs in incubator. The suspension was centrifuged at 3000rpm for 10min and the supernatant was freeze dried by (LyoTrap (NCRRT) USA) and the resulted powder was kept in sealed vial.

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Finally, it could be concluded that our in vitro study indicated that FWGE-nano-Se has high cytotoxcity effect on EAC cells. In addition, our in vivo studies indicated that treatment of mice bearing tumor with FWGE-nano-Se induced tumor growth regression and showed antioxidant activity by increasing the deteriorated levels of GSH ,GPx , CAT and SOD in untreated groups and decreasing their elevated MDA and NO(X). Also, they have no side effect on liver and kidney function parameters.Moreover, it induced apoptosis in Ehrlich carcinoma cells and has antimetastatic effect

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